Immune status in sarcoidosis: one size does not fit all

Professionalism: one size does not fit all.

When a child is born with or acquires special needs, the parents may find some parental tasks more difficult. They may not know how to make their tasks easier, or that some parents find it exceptionally rewarding and meaningful to raise their children with special needs. This piece explores how clinicians might share this potentially life-altering information. It also explores when and why clin...

One-size MAP does not fit all

One-size mean arterial pressure does not fit all The Surviving Sepsis Campaign [1] advocates maintaining a mean arterial pressure (MAP) of at least 65 mm Hg in sepsis patients undergoing resuscitation. Leone and colleagues [2], in an article published in this journal, suggest considering higher MAP targets in the resuscitation of patients with a history of arterial hypertension so they do not p...

Does one size fit all?

ESAs in transplant anemia: one size does not "fit all".

Anemia, a risk factor for cardiovascular events in patients with CKD, is a common problem following transplantation and has been reported in up to 40%of kidney transplant recipients (KTRs).1–3 It is well established that post-transplant anemia (PTA) is associated with poor clinical outcomes. PTA is associated with increased mortality (18% versus 10% over 4 years), an increased risk of acute rej...

Editor's commentary: One size does not fit all.

In this present series of “Mini-Review: Expert Opinions,” leading clinical investigators present their cases for treatment of acute ST-segment elevation myocardial infarction with thrombolytic therapy or percutaneous coronary intervention (PCI). The investigators review relevant studies and their own experience that support their positions. A review of information provided by Drs Armstrong, Col...